Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By reactivating it, scientists were able to help cells recover their youthful behavior. The discovery opens exciting possibilities for anti-aging treatments.

A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells without radiation, enabling nearly complete donor cell replacement. The approach also widens donor eligibility and could soon be applied to other bone marrow failure diseases.

Prenatal exposure to the insecticide chlorpyrifos causes widespread brain abnormalities and poorer motor skills in children. Even after a residential ban, ongoing agricultural use continues to endanger developing brains.

Scientists have pinpointed a “Big Bang” moment in bowel cancer—when cells first evade the immune system. This early immune escape locks in how the cancer will behave as it grows. The discovery could help predict which patients respond to immunotherapy and lead to new vaccine strategies

Rockefeller scientists uncovered how hair follicle stem cells can switch from growing hair to repairing skin when nutrients run low. The key lies in serine, an amino acid that activates a stress signal telling cells to conserve energy. When both injury and low serine occur, stem cells fully pivot to skin repair. The discovery could lead to dietary or medical ways to boost healing.