Rats with naturally high stress levels were far more likely to self-administer cannabis when given access. Behavioral testing showed that baseline stress hormones were the strongest predictor of cannabis-seeking behavior. Lower cognitive flexibility and low endocannabinoid levels also contributed to increased use. The results hint at possible early indicators of vulnerability to drug misuse.

Researchers found that both how often and how much someone drinks significantly shape their cancer risk, even at moderate levels. Vulnerability varies across groups, with genetics, socioeconomic status, obesity, and lifestyle behaviors amplifying harm. The review also uncovered gender differences, beverage-specific risks, and biological pathways that intensify cancer development.

Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to maintain long, healthy telomeres. When RPA malfunctions, telomeres can shorten dangerously, leading to serious diseases.

A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest forms of blood cancer, T-cell acute lymphoblastic leukaemia. By precisely rewriting tiny sections of DNA, scientists at UCL and Great Ormond Street Hospital created universal CAR T-cells capable of targeting the cancer without harming themselves—a long-standing challenge in T-cell–based therapies. Early trial results show deep, long-lasting remissions, including in patients who had exhausted standard treatment options.

Northwestern scientists have created the fastest-ever hepatitis C diagnostic, delivering accurate results in only 15 minutes. The test uses the DASH rapid PCR system, originally developed for COVID, but adapted for whole blood samples. Independent testing showed 100% agreement with existing commercial platforms. Its speed could transform how quickly patients begin treatment.