Fungal infections are becoming deadlier as drug resistance spreads and treatment options stall. Researchers at McMaster University discovered that a molecule called butyrolactol A can dramatically weaken dangerous fungi, allowing existing antifungal drugs to work again. Instead of killing the fungus directly, the molecule sabotages a vital internal system, leaving the pathogen exposed. The breakthrough could help revive an entire class of antifungal medicines once thought obsolete.

New research suggests that consistent aerobic exercise can help keep your brain biologically younger. Adults who exercised regularly for a year showed brains that appeared nearly a year younger than those who didn’t change their habits. The study focused on midlife, a critical window when prevention may offer long-term benefits. Even small shifts in brain age could add up over decades.

A major global study suggests that a hidden mismatch between two common blood tests could quietly signal serious trouble ahead. When results from creatinine and cystatin C—two markers used to assess kidney health—don’t line up, the risk of kidney failure, heart disease, and even death appears to rise sharply. Researchers found that this gap is especially common among hospitalized and older patients, and that relying on just one test may miss early warning signs.

Researchers from New England Biolabs (NEB®) and Yale University describe the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa, an antibiotic-resistant bacterium of global concern, in a new PNAS study. The system is enabled by NEB’s High-Complexity Golden Gate Assembly (HC-GGA) platform. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.

Scientists have discovered that the human brain understands spoken language in a way that closely resembles how advanced AI language models work. By tracking brain activity as people listened to a long podcast, researchers found that meaning unfolds step by step—much like the layered processing inside systems such as GPT-style models.