Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how genes are switched on and off. Scientists found that this “epigenetic drift” follows a clear pattern and appears in both aging intestines and most colon cancers. Some regions age faster than others, forming a patchwork of weakened tissue more prone to degeneration. Encouragingly, researchers showed this drift can be slowed—and partly reversed—by restoring iron levels or key cellular signals.

Sleep isn’t just about feeling rested—it may be one of the strongest predictors of how long you live. Researchers analyzing nationwide data found that insufficient sleep was more closely tied to shorter life expectancy than diet, exercise, or loneliness. The connection was consistent year after year and across most U.S. states. The takeaway is simple but powerful: getting seven to nine hours of sleep may be one of the best things you can do for long-term health.

New research shows that aging blood can accelerate Alzheimer’s-like changes in the brain, while younger blood may offer protection. In mouse experiments, older blood worsened memory performance and increased toxic protein buildup linked to the disease. The study also uncovered widespread changes in brain proteins tied to communication and signaling. The findings point to the blood as a powerful influencer of brain health—and a promising new therapeutic target.

Pancreatic cancer is notoriously hard to treat, often resisting therapies that target its most common mutations. Researchers have now uncovered a hidden three-part loop that fuels tumor growth, involving the cancer drivers SRSF1, AURKA, and MYC. By targeting just one part of this loop with a specially designed molecule, they were able to shut down all three at once. The result was a dramatic loss of tumor cell survival, offering new hope for smarter, more effective treatments.

Sugar-loving mouth bacteria create acids that damage teeth, but arginine can help fight back. In a clinical trial, arginine-treated dental plaque stayed less acidic, became structurally less harmful, and supported more beneficial bacteria. These changes made the biofilms less aggressive after sugar exposure. The results point to arginine as a promising, natural addition to cavity-prevention strategies.