Chronic inflammation may be quietly reshaping the colon and making it more vulnerable to early-onset colorectal cancer. Scientists found that colon tissue in younger patients was stiffer, even in areas that appeared healthy, suggesting these changes may happen before cancer develops. Lab experiments showed that cancer cells grow faster in rigid environments.

Aging immune cells may be sabotaging the body from within. Researchers found that macrophages produce a protein that locks them into a chronic inflammatory state, making infections like sepsis more deadly in older adults. Turning off this signal reduced inflammation and improved survival in older models. The findings hint at future treatments that could dial back harmful immune overreactions.

People with spinal cord injuries often lose movement even though their brains still send the right signals. Researchers tested whether EEG brain scans could capture those signals and reroute them to spinal stimulators. The system can detect when a patient is trying to move, though finer control remains a challenge. Scientists hope future improvements could turn intention into action.

A large, decades-long study suggests that signs of ADHD in childhood may have consequences that extend well beyond school and behavior. Researchers followed nearly 11,000 people from childhood into midlife and found that those with strong ADHD traits at age 10 were more likely to experience multiple physical health problems and health-related disability by their mid-40s.

Chemotherapy’s gut damage turns out to have a surprising upside. By changing nutrient availability in the intestine, it alters gut bacteria and increases levels of a microbial molecule that travels to the bone marrow. This signal reshapes immune cell production, strengthening anti-cancer defenses and making metastatic sites harder for tumors to colonize. Patient data suggest this immune rewiring is linked to better survival.