Tiny ingestible spheres filled with engineered bacteria can detect intestinal bleeding by glowing when they encounter heme. Early tests in mice suggest they could become a quick, noninvasive way to monitor gut disease.

A cutting-edge approach to immunotherapy shows that forcing cancer cells to die through necroptosis can dramatically boost the body's anti-tumor defenses. By combining three existing drugs, scientists reprogrammed malignant B cells so they release danger signals that rally immune cells to fully eliminate leukemia in preclinical models.

Researchers created a dissolvable microneedle patch that delivers IL-4 directly to damaged heart tissue, jump-starting repair after a heart attack. The targeted approach shifts immune cells into a healing mode while improving communication between heart muscle and blood vessel cells. It avoids the systemic risks of IL-4 injections and shows promise for future minimally invasive treatment.

Researchers have recreated a miniature human bone marrow system that mirrors the real structure found inside our bones. The model includes the full mix of cells and signals needed for blood production and even maintains this process for weeks. It could transform how scientists study blood cancers and test new drugs. In the future, it may support more personalized treatment strategies.

A nationwide analysis has uncovered how sprawling fossil fuel infrastructure sits surprisingly close to millions of American homes. The research shows that 46.6 million people live within about a mile of wells, refineries, pipelines, storage sites, or transport facilities. Many of these locations release pollutants that may affect nearby communities, yet mid-supply-chain sites have rarely been studied. The findings reveal major gaps in understanding how this hidden network affects health.